Antibodies against immature virions are not a discriminating factor for dengue disease severity.

• Main Authors: Izabela A Rodenhuis-Zybert (Author), Júlia M da Silva Voorham (Author), Silvia Torres (Author), Denise van de Pol (Author), Jolanda M Smit (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Humoral immunity plays an important role in controlling dengue virus (DENV) infection. Antibodies (Abs) developed during primary infection protect against subsequent infection with the same dengue serotype, but can enhance disease following secondary infection with a heterologous serotype. A DENV vi...