Matrine Protects Against MCD-Induced Development of NASH via Upregulating HSP72 and Downregulating mTOR in a Manner Distinctive From Metformin

• Hauptverfasser: Ali Mahzari (Verfasst von), Songpei Li (Verfasst von), Xiu Zhou (Verfasst von), Dongli Li (Verfasst von), Sherouk Fouda (Verfasst von), Majid Alhomrani (Verfasst von), Wala Alzahrani (Verfasst von), Stephen R. Robinson (Verfasst von), Ji-Ming Ye (Verfasst von)
• Format: Buch
• Veröffentlicht: Frontiers Media S.A., 2019-04-01T00:00:00Z.
• Schlagworte: article
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The present study investigated the effects of matrine on non-alcoholic steatohepatitis (NASH) in mice induced by a methionine choline-deficient (MCD) diet and the mechanism involved. The study was performed in C57B/6J mice fed a MCD diet for 6 weeks to induce NASH with or without the treatment of ma...