The Protective Effect of Ethanolic Extract of Mentha spicata Against Irinotecan-Induced Mucositis in mice

• Hoofdauteurs: Aliaa Abdul sattar Abdul jabbar (Auteur), Sarmed H. Kathem (Auteur)
• Formaat: Boek
• Gepubliceerd in: College of Pharmacy University of Baghdad, 2019-06-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Irinotecan induced-mucositis is an inflammatory event of intestine caused by an increase in concentration of active metabolite 7­ethyl­10-hydroxycamptothecin (SN­38) in the intestine. Irinotecan must first be converted by a carboxylesterase (CES) to the active metabolite (SN­38), which is subsequent...