Integrated analysis of Dendrobium nobile extract Dendrobin A against pancreatic ductal adenocarcinoma based on network pharmacology, bioinformatics, and validation experiments

• Main Authors: Xiaoqing Xu (Author), Yaping Yu (Author), Li Yang (Author), Bingshu Wang (Author), Yonghao Fan (Author), Banzhan Ruan (Author), Xiaodian Zhang (Author), Haofu Dai (Author), Wenli Mei (Author), Wei Jie (Author), Shaojiang Zheng (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background:Dendrobium nobile (D. nobile), a traditional Chinese medicine, has received attention as an anti-tumor drug, but its mechanism is still unclear. In this study, we applied network pharmacology, bioinformatics, and in vitro experiments to explore the effect and mechanism of Dendrobin A, the...