The Synergistic Combination of Cisplatin and Piperine Induces Apoptosis in MCF-7 Cell Line

• Main Authors: Abolfazl Fattah (Author), Ali Morovati (Author), Zahra Niknam (Author), Ladan Mashouri (Author), Amirhooman Asadi (Author), Shirin Tvangar Rizi (Author), Mojtaba Abbasi (Author), Fatemeh Shakeri (Author), Omid Abazari (Author)
• Format: Book
• Published: Tehran University of Medical Sciences, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Piperine is a natural compound obtained from the Piper nigrum that exhibits anti-proliferative and anti-cancer activity in cancer cell lines. We analyzed the cytotoxic effect of piperine combined with cisplatin compound in the human MCF-7 breast cancer cell line and the underlying mechan...