A comprehensive evaluation in clinic and physiologically‐based pharmacokinetic modeling and simulation to confirm lack of cytochrome P450-mediated drug-drug interaction potential for pomotrelvir
Abstract Pomotrelvir is a new chemical entity and potent direct‐acting antiviral inhibitor of the main protease of coronaviruses. Here the cytochrome P450 (CYP)-mediated drug-drug interaction (DDI) potential of pomotrelvir was evaluated for major CYP isoforms, starting with in vitro assays followed...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Wiley,
2023-10-01T00:00:00Z.
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| Online Access: | Connect to this object online. |
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