Drug-Rich Phases Induced by Amorphous Solid Dispersion: Arbitrary or Intentional Goal in Oral Drug Delivery?

• Главные авторы: Kaijie Qian (Автор), Lorenzo Stella (Автор), David S. Jones (Автор), Gavin P. Andrews (Автор), Huachuan Du (Автор), Yiwei Tian (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2021-06-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Among many methods to mitigate the solubility limitations of drug compounds, amorphous solid dispersion (ASD) is considered to be one of the most promising strategies to enhance the dissolution and bioavailability of poorly water-soluble drugs. The enhancement of ASD in the oral absorption of drugs...