Industrial application of heat- and mass balance model for fluid-bed granulation for technology transfer and design space exploration

This work demonstrates the application of state-of-the-art modeling techniques in pharmaceutical manufacturing for fluid bed granulation at varying scales to successfully predict process conditions and ultimately replace experiments during a technology transfer of five products. We describe a mathem...

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Bibliographic Details
Main Authors: David R. Ochsenbein (Author), Matthew Billups (Author), Bingbing Hong (Author), Elisabeth Schäfer (Author), Alexander J. Marchut (Author), Olav K. Lyngberg (Author)
Format: Book
Published: Elsevier, 2019-12-01T00:00:00Z.
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