Population Exposure‐Response Modeling of Naloxegol in Patients With Noncancer‐Related Pain and Opioid‐Induced Constipation

• Asıl Yazarlar: N Al‐Huniti (Yazar), JC Nielsen (Yazar), MM Hutmacher (Yazar), J Lappalainen (Yazar), K Cantagallo (Yazar), M Sostek (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Wiley, 2016-07-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Naloxegol is a polyethylene glycol derivative of naloxone approved in the US as a once‐daily oral treatment for opioid‐induced constipation (OIC) in adults with chronic noncancer pain. Population exposure-response models were constructed based on data from two phase III studies comprising 1,331 adul...