Periodontitis and increase in circulating oxidative stress

• Main Authors: Takaaki Tomofuji (Author), Koichiro Irie (Author), Toshihiro Sanbe (Author), Tetsuji Azuma (Author), Daisuke Ekuni (Author), Naofumi Tamaki (Author), Tatsuo Yamamoto (Author), Manabu Morita (Author)
• Format: Book
• Published: Elsevier, 2009-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Reactive oxygen species (ROS) are products of normal cellular metabolism. However, excessive production of ROS oxidizes DNA, lipids and proteins, inducing tissue damage. Studies have shown that periodontitis induces excessive ROS production in periodontal tissue. When periodontitis develops, ROS pro...