Synergistic effects of anlotinib and DDP on breast cancer: targeting the VEGF/JAK2/STAT3 axis

• Main Authors: Hongmei Zhang (Author), Chunling Liu (Author), Ye Jin (Author), Zheng Wang (Author), Yi Guan (Author), Zhenxian Jia (Author), Tong Cui (Author), Zhi Zhang (Author), Xuemei Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundAnlotinib, a highly selective inhibitor of VEGFR2, has demonstrated significant anti-tumor effects in various cancers. However, its potential synergistic effects with DDP (cisplatin) in breast cancer (BRCA) remain to be fully elucidated. This study aims to discover the therapeutic efficacy...