Impaired immunoproteasomal function exacerbates renal ischemia-reperfusion injury

• Main Authors: Yasushi Ishii (Author), Aya Fukui-Miyazaki (Author), Sari Iwasaki (Author), Takahiro Tsuji (Author), Kiyohiko Hotta (Author), Hajime Sasaki (Author), Shimpei Nakagawa (Author), Takuma Yoshida (Author), Eri Murata (Author), Koji Taniguchi (Author), Nobuo Shinohara (Author), Akihiro Ishizu (Author), Masanori Kasahara (Author), Utano Tomaru (Author)
• Format: Book
• Published: Elsevier, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxidative stress caused by reactive oxygen species (ROS) is involved in the pathogenesis of renal ischemia-reperfusion injury (I/R injury), a major cause of acute kidney injury and delayed graft function (DGF). DGF is an early transplant complication that worsens graft prognosis and patient survival...