A Lipid Mediator Hepoxilin A3 Is a Natural Inducer of Neutrophil Extracellular Traps in Human Neutrophils

• المؤلفون الرئيسيون: David N. Douda (مؤلف), Hartmut Grasemann (مؤلف), Cecil Pace-Asciak (مؤلف), Nades Palaniyar (مؤلف)
• التنسيق: كتاب
• منشور في: Hindawi Limited, 2015-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Pulmonary exacerbations in cystic fibrosis airways are accompanied by inflammation, neutrophilia, and mucous thickening. Cystic fibrosis sputum contains a large amount of uncleared DNA contributed by neutrophil extracellular trap (NET) formation from neutrophils. The exact mechanisms of the inductio...