Development and Characterisation of Antibody-Based Optical Imaging Probes for Inflammatory Bowel Disease

• Main Authors: Matthijs David Linssen (Author), Wouter Tjerk Rudolph Hooghiemstra (Author), Annelies Jorritsma-Smit (Author), Derk Pieter Allersma (Author), Gerard Dijkstra (Author), Wouter Bastiaan Nagengast (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Monoclonal antibodies are an important addition to the medicinal treatment paradigm for IBD patients. While effective, these agents show a high degree of primary and secondary non-response, and methods to predict response are highly desired. Information on drug distribution at the target level is of...