Resveratrol, a SIRT1 activator, attenuates aging-associated alterations in skeletal muscle and heart in mice

• मुख्य लेखकों: Ryusuke Hosoda (लेखक), Ryuta Nakashima (लेखक), Masaki Yano (लेखक), Naotoshi Iwahara (लेखक), Seidai Asakura (लेखक), Iyori Nojima (लेखक), Yukika Saga (लेखक), Risa Kunimoto (लेखक), Yoshiyuki Horio (लेखक), Atsushi Kuno (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2023-06-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Aging is associated with impairment of multiple organs, including skeletal muscle and heart. In this study, we investigated whether resveratrol, an activator of an NAD+-dependent protein deacetylase Sirtuin-1 (SIRT1), attenuates age-related sarcopenia and cardiomyocyte hypertrophy in mice. Treatment...