Resveratrol, a SIRT1 activator, attenuates aging-associated alterations in skeletal muscle and heart in mice

Resveratrol, a SIRT1 activator, attenuates aging-associated alterations in skeletal muscle and heart in mice

Aging is associated with impairment of multiple organs, including skeletal muscle and heart. In this study, we investigated whether resveratrol, an activator of an NAD+-dependent protein deacetylase Sirtuin-1 (SIRT1), attenuates age-related sarcopenia and cardiomyocyte hypertrophy in mice. Treatment...

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Main Authors: Ryusuke Hosoda (Author), Ryuta Nakashima (Author), Masaki Yano (Author), Naotoshi Iwahara (Author), Seidai Asakura (Author), Iyori Nojima (Author), Yukika Saga (Author), Risa Kunimoto (Author), Yoshiyuki Horio (Author), Atsushi Kuno (Author)
Format: Book
Published: Elsevier, 2023-06-01T00:00:00Z.
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