Trypanosoma brucei glycogen synthase kinase-3, a target for anti-trypanosomal drug development: a public-private partnership to identify novel leads.

• Asıl Yazarlar: Richard O Oduor (Yazar), Kayode K Ojo (Yazar), Gareth P Williams (Yazar), Francois Bertelli (Yazar), James Mills (Yazar), Louis Maes (Yazar), David C Pryde (Yazar), Tanya Parkinson (Yazar), Wesley C Van Voorhis (Yazar), Tod P Holler (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Public Library of Science (PLoS), 2011-04-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Trypanosoma brucei, the causative agent of Human African Trypanosomiasis (HAT), expresses two proteins with homology to human glycogen synthase kinase 3β (HsGSK-3) designated TbruGSK-3 short and TbruGSK-3 long. TbruGSK-3 short has previously been validated as a potential drug target and since this e...