MASP-1 and MASP-3 Bind Directly to Aspergillus fumigatus and Promote Complement Activation and Phagocytosis

• Main Authors: Anne Rosbjerg (Author), Reinhard Würzner (Author), Peter Garred (Author), Mikkel-Ole Skjoedt (Author)
• פורמט: ספר
• יצא לאור: Karger Publishers, 2021-03-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Activation of the complement system is mediated by the interaction between pathogens and pattern recognition molecules (PRMs); mannose-binding lectin (MBL), ficolins, and collectin-10/-11 from the lectin pathway and C1q from the classical pathway. Lectin pathway activation specifically depends on pr...