An insight on the role of genetic testing of RUNX1: A key transcriptional gene in familial platelet disorder with predisposition to acute myeloid leukemia
Background: Familial platelet disorder (FPD) with predisposition to acute myeloid leukemia (AML) is an autosomal dominant disease of the hematopoietic system that is caused by heterozygous mutations in RUNX1 gene. RUNX1 is frequently involved in the pathogenesis of sporadic leukemia and myelodysplas...
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Main Authors: | Intezar Mehdi (Author), K. Ramya (Author), T.L. Suma (Author), Ashraf Mannan (Author), M.L. Sheela (Author), Shanmukh Kattragada (Author), B.S. Ajaikumar (Author), Mithua Ghosh (Author) |
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Format: | Book |
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Elsevier,
2023-06-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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