Relationship between antibody susceptibility and lipopolysaccharide O-antigen characteristics of invasive and gastrointestinal nontyphoidal Salmonellae isolates from Kenya.

• Main Authors: Robert S Onsare (Author), Francesca Micoli (Author), Luisa Lanzilao (Author), Renzo Alfini (Author), Chinyere K Okoro (Author), Anne W Muigai (Author), Gunturu Revathi (Author), Allan Saul (Author), Samuel Kariuki (Author), Calman A MacLennan (Author), Simona Rondini (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Nontyphoidal Salmonellae (NTS) cause a large burden of invasive and gastrointestinal disease among young children in sub-Saharan Africa. No vaccine is currently available. Previous reports indicate the importance of the O-antigen of Salmonella lipopolysaccharide for virulence and resistan...