Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity

As regioisomers/bioisosteres of 1a, a 4-phenylbenzamide tranylcypromine (TCP) derivative previously disclosed by us, we report here the synthesis and biological evaluation of some (hetero)arylbenzoylamino TCP derivatives 1b-6, in which the 4-phenyl moiety of 1a was shifted at the benzamide C3 positi...

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Ngā kaituhi matua: Rossella Fioravanti (Author), Veronica Rodriguez (Author), Jonatan Caroli (Author), Ugo Chianese (Author), Rosaria Benedetti (Author), Elisabetta Di Bello (Author), Beatrice Noce (Author), Clemens Zwergel (Author), Davide Corinti (Author), Dolores Viña (Author), Lucia Altucci (Author), Andrea Mattevi (Author), Sergio Valente (Author), Antonello Mai (Author)
Hōputu: Pukapuka
I whakaputaina: Taylor & Francis Group, 2022-12-01T00:00:00Z.
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