表紙画像

Heterocycle-containing tranylcypromine derivatives endowed with high anti-LSD1 activity

As regioisomers/bioisosteres of 1a, a 4-phenylbenzamide tranylcypromine (TCP) derivative previously disclosed by us, we report here the synthesis and biological evaluation of some (hetero)arylbenzoylamino TCP derivatives 1b-6, in which the 4-phenyl moiety of 1a was shifted at the benzamide C3 positi...

保存先:

書誌詳細
主要な著者:	Rossella Fioravanti (著者), Veronica Rodriguez (著者), Jonatan Caroli (著者), Ugo Chianese (著者), Rosaria Benedetti (著者), Elisabetta Di Bello (著者), Beatrice Noce (著者), Clemens Zwergel (著者), Davide Corinti (著者), Dolores Viña (著者), Lucia Altucci (著者), Andrea Mattevi (著者), Sergio Valente (著者), Antonello Mai (著者)
フォーマット:	図書
出版事項:	Taylor & Francis Group, 2022-12-01T00:00:00Z.
主題:	article
オンライン･アクセス:	Connect to this object online.
タグ:	タグ追加タグなし, このレコードへの初めてのタグを付けませんか!

類似資料

LSD1 inhibitors for cancer treatment: Focus on multi-target agents and compounds in clinical trials
著者:: Beatrice Noce, 等
出版事項: (2023)

LSD1 inhibition by tranylcypromine hydrochloride reduces alkali burn-induced corneal neovascularization and ferroptosis by suppressing HIF-1α pathway
著者:: Qian Deng, 等
出版事項: (2024)

3-Chloro-N'-(2-hydroxybenzylidene) benzohydrazide: An LSD1-Selective Inhibitor and Iron-Chelating Agent for Anticancer Therapy
著者:: Federica Sarno, 等
出版事項: (2018)

Strategies that regulate LSD1 for novel therapeutics
著者:: Meng Li, 等
出版事項: (2024)

Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group
著者:: Pasquale Linciano, 等
出版事項: (2021)

Biological and therapeutic role of LSD1 in Alzheimer's diseases
著者:: Yu Li, 等
出版事項: (2022)

Natural products as LSD1 inhibitors for cancer therapy
著者:: Yuan Fang, 等
出版事項: (2021)

Developmental Origins and Nephron Endowment in Hypertension
著者:: Shari Gurusinghe, 等
出版事項: (2017)

Quantification of LSD in illicit samples by high performance liquid chromatography
著者:: Pablo Alves Marinho, 等
出版事項: (2010)

Benzimidazole derivatives endowed with potent antileishmanial activity
著者:: Michele Tonelli, 等
出版事項: (2018)

Montelukast and Acute Coronary Syndrome: The Endowed Drug
著者:: Basil Mohammed Alomair, 等
出版事項: (2022)

Heterocycles Synthesis and Biological Activities
出版事項: (2020)

Selenium-Containing Agents Acting on Cancer-A New Hope?
著者:: Sabrina Garbo, 等
出版事項: (2022)

The Endowed Charities of Kensington: By Whom Bequeathed, and How Administered
著者:: Daniel, Edward Morton, 1848-

Green Synthesis of Heterocycles
出版事項: (2020)

Metabolite profiling of ascidian Styela plicata using LC-MS with multivariate statistical analysis and their antitumor activity
著者:: Satheesh Kumar Palanisamy, 等
出版事項: (2017)

BUSINESS GAMES AS THE FORM OF ENDOWED CHILDREN PREPARATION TO RESEARCH ACTIVITY
著者:: N.I. Polikhun, 等
出版事項: (2010)

Efectos de la heroína, marihuana, LSD y metadona sobre la reproducción
著者:: G. Pardo, 等
出版事項: (1986)

Discovery of novel sulphonamide hybrids that inhibit LSD1 against bladder cancer cells
著者:: Jia Liu, 等
出版事項: (2022)

Histone demethylase LSD1-mediated repression of GATA-2 is critical for erythroid differentiation
著者:: Guo Y, 等
出版事項: (2015)

LSD Increases Primary Process Thinking via Serotonin 2A Receptor Activation
著者:: Rainer Kraehenmann, 等
出版事項: (2017)

Modern Strategies for Heterocycle Synthesis
出版事項: (2021)

Strategies for the Synthesis of Heterocycles and Their Applications
出版事項: (2023)

Bioactive Marine Heterocyclic Compounds
出版事項: (2021)

Role of the 5-HT2A Receptor in Acute Effects of LSD on Empathy and Circulating Oxytocin
著者:: Friederike Holze, 等
出版事項: (2021)

Drugs in therapy. LSD, MDMA, marijuana, psilocybin, designer drugs and its potential in modern medicine.
著者:: Agata Tadeja
出版事項: (2020)

MicroRNA-155 Participates in the Expression of LSD1 and Proinflammatory Cytokines in Rheumatoid Synovial Cells
著者:: Ziliang Yu, 等
出版事項: (2020)

Comparison of the Characteristics of Endowment-educational Complexes in Ilkhanid and Timurid Period of Iran
著者:: Javad Rajabi Mandi, 等
出版事項: (2021)

Current View on Major Natural Compounds Endowed with Antibacterial and Antiviral Effects
著者:: Roberto Arrigoni, 等
出版事項: (2024)

Heterocyclic Compounds from Marine Organisms
出版事項: (2022)

Heterocycles in Peptidomimetics and Pseudopeptides: Design and Synthesis
著者:: Ambra Guarnaccio, 等
出版事項: (2012)

Antitumor properties of certain spirooxindoles towards hepatocellular carcinoma endowed with antioxidant activity
著者:: Sara T. Al-Rashood, 等
出版事項: (2020)

Discovery of novel FGF trap small molecules endowed with anti-myeloma activity
著者:: Sara Taranto, 等
出版事項: (2024)

Application of Small Epigenetic Modulators in Pediatric Medulloblastoma
著者:: Clemens Zwergel, 等
出版事項: (2018)

LSD Administered as a Single Dose Reduces Alcohol Consumption in C57BL/6J Mice
著者:: Kenneth Alper, 等
出版事項: (2018)

A state-of-the-art review on LSD1 and its inhibitors in breast cancer: Molecular mechanisms and therapeutic significance
著者:: Guan-Jun Yang, 等
出版事項: (2022)

Metal Promoted Cyclocarbonylation Reactions in the Synthesis of Heterocycles
出版事項: (2022)

Five-Membered Heterocyclic Ring Via Dichalcones
著者:: N. Ahmad, 等
出版事項: (2013)

Cytotoxicity study of dimethylisatin and its heterocyclic derivatives
著者:: Mohammad Mamun Hossain, 等
出版事項: (2007)

Cytotoxicity study of dimethylisatin and its heterocyclic derivatives
著者:: Mohammad Mamun Hossain, Nazrul Islam, Rahat Khan and Md. Rabiul Islam
出版事項: (2007)