Sildenafil and bosentan plasma concentrations in a human immunodeficiency virus-infected patient with pulmonary arterial hypertension treated with ritonavir-boosted protease inhibitor

• Hoofdauteurs: Pierangelo Chinello (Auteur), Stefania Cicalini (Auteur), Simona Pichini (Auteur), Roberta Pacifici (Auteur), Massimo Tempestilli (Auteur), Maria P. Cicini (Auteur), Leopoldo P. Pucillo (Auteur), Nicola Petrosillo (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2015-03-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Sildenafil and bosentan are increasingly used for the treatment of pulmonary arterial hypertension (PAH) in HIV-infected patients. However, concerns exist about pharmacokinetic interactions among sildenafil, bosentan and antiretroviral drugs, including protease inhibitors (PI). We describe here the...