Secondary donor-derived humanized CD19-modified CAR-T cells induce remission in relapsed/refractory mixed phenotype acute leukemia after allogeneic hematopoietic stem cell transplantation: a case report

• Main Authors: Meng-Yun Li (Author), Zhi-Hong Lin (Author), Ming-Ming Hu (Author), Li-Qing Kang (Author), Xiao-xia Wu (Author), Qi-wei Chen (Author), Xin Kong (Author), Jian Zhang (Author), Hui-Ying Qiu (Author), De-Pei Wu (Author)
• Format: Book
• Published: BMC, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Mixed phenotype acute leukemia (MPAL) is a rare leukemia and is regarded as a high-risk entity with a poor prognosis. Induction therapy of an acute lymphoblastic leukemia type or hybrid regimen and hematopoietic stem cell transplantation has been recommended for MPAL. However, th...