Behind the Adaptive and Resistance Mechanisms of Cancer Stem Cells to TRAIL

• Main Authors: Adriana G. Quiroz-Reyes (Author), Paulina Delgado-Gonzalez (Author), Jose Francisco Islas (Author), Juan Luis Delgado Gallegos (Author), Javier Humberto Martínez Garza (Author), Elsa N. Garza-Treviño (Author)
• Format: Book
• Published: MDPI AG, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), also known as Apo-2 ligand (Apo2L), is a member of the TNF cytokine superfamily. TRAIL has been widely studied as a novel strategy for tumor elimination, as cancer cells overexpress TRAIL death receptors, inducing apoptosis and i...