Evaluation of the stability of Polymyxin B in saline and glucose solutions using LC-MS/MS

• Main Authors: Juliana Kich Castilhos (Author), Thaís Luise Dillenburg (Author), Marina Venzon Antunes (Author), Letícia Scribel (Author), Alexandre Prehn Zavascki (Author), Rafael Linden (Author), Simone Gasparin Verza (Author)
• Format: Book
• Published: Universidade de São Paulo, 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Polymyxins are a group of antibacterial substances and have remained the drugs of choice for treatment of resistant Gram-negative bacilli. Polymyxin B is administered by intravenous infusion and requires the reconstitution of lyophilized powder with 0.9% saline or 5% glucose solutions. To date, ther...