Evaluation of the stability of Polymyxin B in saline and glucose solutions using LC-MS/MS

• Váldodahkkit: Juliana Kich Castilhos (Dahkki), Thaís Luise Dillenburg (Dahkki), Marina Venzon Antunes (Dahkki), Letícia Scribel (Dahkki), Alexandre Prehn Zavascki (Dahkki), Rafael Linden (Dahkki), Simone Gasparin Verza (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Universidade de São Paulo, 2020-03-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Polymyxins are a group of antibacterial substances and have remained the drugs of choice for treatment of resistant Gram-negative bacilli. Polymyxin B is administered by intravenous infusion and requires the reconstitution of lyophilized powder with 0.9% saline or 5% glucose solutions. To date, ther...