Rapid, simple and stability-indicating determination of polyhexamethylene biguanide in liquid and gel-like dosage forms by liquid chromatography with diode-array detection

• Main Authors: Markus Küsters (Author), Sören Beyer (Author), Stephan Kutscher (Author), Harald Schlesinger (Author), Michael Gerhartz (Author)
• Format: Book
• Published: Elsevier, 2013-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A rapid and simple method for the determination of polyhexamethylene biguanide (polyhexanide, PHMB) in liquid and gel-like pharmaceutical formulations by means of high performance liquid chromatography coupled to diode-array detection (HPLCâDAD) was developed. Best separation was achieved using a cy...