Establishing clinically meaningful within-individual improvement thresholds for eight patient-reported outcome measures in people with relapsing-remitting multiple sclerosis

• Main Authors: Nupur Greene (Author), Stéphane Quéré (Author), Denise P. Bury (Author), Flora Mazerolle (Author), Manal M'Hari (Author), Angély Loubert (Author), Antoine Regnault (Author), Keiko Higuchi (Author)
• Format: Book
• Published: SpringerOpen, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background As disease-modifying therapies do not reverse the course of multiple sclerosis (MS), assessment of therapeutic success involves documenting patient-reported outcomes (PROs) concerning health-related quality of life, disease and treatment-related symptoms, and the impact of sympto...