Epigenetic Reader Bromodomain Containing Protein 2 Facilitates Pathological Cardiac Hypertrophy via Regulating the Expression of Citrate Cycle Genes

• Main Authors: Zhirong Lin (Author), Zhenzhen Li (Author), Zhen Guo (Author), Yanjun Cao (Author), Jingyan Li (Author), Peiqing Liu (Author), Zhuoming Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The bromodomain and extra-terminal domain proteins (BETs) family serve as epigenetic "readers", which recognize the acetylated histones and recruit transcriptional regulator complexes to chromatin, eventually regulating gene transcription. Accumulating evidences demonstrate that pan BET in...