Coupled CRC 2D and ALI 3D Cultures Express Receptors of Emerging Viruses and Are More Suitable for the Study of Viral Infections Compared to Conventional Cell Lines

• Main Authors: Siyu Xia (Author), Jun Liu (Author), Yan Yang (Author), Ming Wu (Author), Lina Ye (Author), Si Chen (Author), Tao Zhang (Author), Zhihong Zeng (Author), Kang Zhang (Author), Kaihong Cai (Author), Xiang Long (Author), Wenbin Gao (Author), Shisong Fang (Author), Hui Li (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Infections of emerging and reemerging viruses (SARS-CoVs, influenza H1N1, etc.) largely and globally affect human health. Animal models often fail to reflect a physiological status because of species tropism of virus infection. Conventional cell lines are usually genetically and phenotypically diffe...