Nardosinone Suppresses RANKL-Induced Osteoclastogenesis and Attenuates Lipopolysaccharide-Induced Alveolar Bone Resorption

• Main Authors: Chenguang Niu (Author), Fei Xiao (Author), Keyong Yuan (Author), XuChen Hu (Author), Wenzhen Lin (Author), Rui Ma (Author), Xiaoling Zhang (Author), Zhengwei Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Periodontitis is a chronic inflammatory disease that damages the integrity of the tooth-supporting tissues, known as the periodontium, and comprising the gingiva, periodontal ligament and alveolar bone. In this study, the effects of nardosinone (Nd) on bone were tested in a model of lipopolysacchari...