A Novel Human Organic Anion Transporter NPT4 Mediates the Transport of Ochratoxin A

• Glavni autori: Promsuk Jutabha (Autor), Naohiko Anzai (Autor), Keitaro Hayashi (Autor), Mariko Domae (Autor), Kohsuke Uchida (Autor), Hitoshi Endou (Autor), Hiroyuki Sakurai (Autor)
• Format: Knjiga
• Izdano: Elsevier, 2011-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract.: In the present study, we investigated the transport of nephrotoxic mycotoxin ochratoxin A (OTxA) by a novel human organic anion transporter hNPT4 using the Xenopus oocyte expression system. hNPT4 mediated time- and concentration-dependent uptake of OTxA (Km: 802.8 μM) in a pH- and voltage...