Transcriptomic analysis supports a role for the nervous system in regulating growth and development of Fasciola hepatica juveniles.

• Main Authors: Emily Robb (Author), Erin M McCammick (Author), Duncan Wells (Author), Paul McVeigh (Author), Erica Gardiner (Author), Rebecca Armstrong (Author), Paul McCusker (Author), Angela Mousley (Author), Nathan Clarke (Author), Nikki J Marks (Author), Aaron G Maule (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fasciola spp. liver flukes have significant impacts in veterinary and human medicine. The absence of a vaccine and increasing anthelmintic resistance threaten sustainable control and underscore the need for novel flukicides. Functional genomic approaches underpinned by in vitro culture of juvenile F...