Xuebijing injection inhibited neutrophil extracellular traps to reverse lung injury in sepsis mice via reducing Gasdermin D

• Główni autorzy: Ting Shang (Autor), Zhi-Sen Zhang (Autor), Xin-Tong Wang (Autor), Jing Chang (Autor), Meng-En Zhou (Autor), Ming Lyu (Autor), Shuang He (Autor), Jian Yang (Autor), Yan-Xu Chang (Autor), Yuefei Wang (Autor), Ming-Chun Li (Autor), Xiumei Gao (Autor), Yan Zhu (Autor), Yuxin Feng (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2022-11-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The mortality of sepsis and septic shock remains high worldwide. Neutrophil extracellular traps (NETs) release is a major cause of organ failure and mortality in sepsis. Targeting Gasdermin D (GSDMD) can restrain NETs formation, which is promising for sepsis management. However, no medicine is ident...