In Silico Prediction of Plasma Concentrations of Fluconazole Capsules with Different Dissolution Profiles and Bioequivalence Study Using Population Simulation

• Auteurs principaux: Marcelo Dutra Duque (Auteur), Daniela Amaral Silva (Auteur), Michele Georges Issa (Auteur), Valentina Porta (Auteur), Raimar Löbenberg (Auteur), Humberto Gomes Ferraz (Auteur)
• Format: Livre
• Publié: MDPI AG, 2019-05-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

A biowaiver is accepted by the Brazilian Health Surveillance Agency (ANVISA) for immediate-release solid oral products containing Biopharmaceutics Classification System (BCS) class I drugs showing rapid drug dissolution. This study aimed to simulate plasma concentrations of fluconazole capsules with...