Rescued Chondrogenesis of Mesenchymal Stem Cells under Interleukin 1 Challenge by Foamyviral Interleukin 1 Receptor Antagonist Gene Transfer

• Main Authors: Nicole Armbruster (Author), Jennifer Krieg (Author), Manuel Weißenberger (Author), Carsten Scheller (Author), Andre F. Steinert (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2017-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Background: Mesenchymal stem cells (MSCs) and their chondrogenic differentiation have been extensively investigated in vitro as MSCs provide an attractive source besides chondrocytes for cartilage repair therapies. Here we established prototype foamyviral vectors (FVV) that are derived from apathoge...