Nicotinamide riboside kinase 1 protects against diet and age-induced pancreatic β-cell failure

• Päätekijät: Angelique Cercillieux (Tekijä), Joanna Ratajczak (Tekijä), Magali Joffraud (Tekijä), José Luis Sanchez-Garcia (Tekijä), Guillaume Jacot (Tekijä), Alix Zollinger (Tekijä), Sylviane Métairon (Tekijä), Judith Giroud-Gerbetant (Tekijä), Marie Rumpler (Tekijä), Eleonora Ciarlo (Tekijä), Miriam Valera-Alberni (Tekijä), Audrey Sambeat (Tekijä), Carles Canto (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Elsevier, 2022-12-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Objective: Disturbances in NAD+ metabolism have been described as a hallmark for multiple metabolic and age-related diseases, including type 2 diabetes. While alterations in pancreatic β-cell function are critical determinants of whole-body glucose homeostasis, the role of NAD+ metabolism in the end...