The protease activated receptor 2 - CCAAT/enhancer-binding protein beta - SerpinB3 axis inhibition as a novel strategy for the treatment of non-alcoholic steatohepatitis

• मुख्य लेखकों: Gianmarco Villano (लेखक), Erica Novo (लेखक), Cristian Turato (लेखक), Santina Quarta (लेखक), Mariagrazia Ruvoletto (लेखक), Alessandra Biasiolo (लेखक), Francesca Protopapa (लेखक), Monica Chinellato (लेखक), Andrea Martini (लेखक), Elisabetta Trevellin (लेखक), Marnie Granzotto (लेखक), Stefania Cannito (लेखक), Laura Cendron (लेखक), Silvia De Siervi (लेखक), Maria Guido (लेखक), Maurizio Parola (लेखक), Roberto Vettor (लेखक), Patrizia Pontisso (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2024-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Objective: The serine protease inhibitor SerpinB3 has been described as critical mediator of liver fibrosis and it has been recently proposed as an additional hepatokine involved in NASH development and insulin resistance. Protease Activated Receptor 2 has been identified as a novel regulator of hep...