Pharmacokinetic interaction of voriconazole and clarithromycin in Pakistani healthy male volunteers: a single dose, randomized, crossover, open-label study

Background: Voriconazole an antifungal drug, has a potential for drug-drug interactions (DDIs) with administered drugs. Clarithromycin is a Cytochromes P450 CYP (3A4 and 2C19) enzyme inhibitor, and voriconazole is a substrate and inhibitor of these two enzymes. Being a substrate of the same enzyme f...

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Egile Nagusiak: Mehwish Mushtaq (Egilea), Kshaf Fatima (Egilea), Aneeqa Ahmad (Egilea), Osama Mohamed Ibrahim (Egilea), Muhammad Faheem (Egilea), Yasar Shah (Egilea)
Formatua: Liburua
Argitaratua: Frontiers Media S.A., 2023-06-01T00:00:00Z.
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