Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq

Parent-of-origin detection and chromosome-scale haplotyping using long-read DNA methylation sequencing and Strand-seq

Summary: Hundreds of loci in human genomes have alleles that are methylated differentially according to their parent of origin. These imprinted loci generally show little variation across tissues, individuals, and populations. We show that such loci can be used to distinguish the maternal and patern...

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Main Authors: Vahid Akbari (Author), Vincent C.T. Hanlon (Author), Kieran O'Neill (Author), Louis Lefebvre (Author), Kasmintan A. Schrader (Author), Peter M. Lansdorp (Author), Steven J.M. Jones (Author)
Format: Book
Published: Elsevier, 2023-01-01T00:00:00Z.
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3rd Floor Main Library

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