Identification and functional analysis of choline transporter in tongue cancer: A novel molecular target for tongue cancer therapy

• Main Authors: Ryohta Nishiyama (Author), Fumiaki Nagashima (Author), Beniko Iwao (Author), Yuiko Kawai (Author), Kana Inoue (Author), Arisa Midori (Author), Tsuyoshi Yamanaka (Author), Hiroyuki Uchino (Author), Masato Inazu (Author)
• Format: Book
• Published: Elsevier, 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We examined the functional characteristics of choline uptake in human tongue carcinoma using the cell line HSC-3. Furthermore, we explored the possible correlation between the inhibition of choline uptake and apoptotic cell death. Both choline transporter-like protein 1 (CTL1) and CTL2 mRNAs and pro...