Shortening of Zika virus CD-loop reduces neurovirulence while preserving antigenicity.

• Main Authors: Kenneth H Dinnon Iii (Author), Emily N Gallichotte (Author), Ethan J Fritch (Author), Vineet D Menachery (Author), Ralph S Baric (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Zika virus (ZIKV) is a mosquito-borne positive sense RNA virus. Recently, ZIKV emerged into the Western hemisphere as a human health threat, with severe disease associated with developmental and neurological complications. The structural envelope protein of ZIKV and other neurotropic flaviviruses co...