Methylation Pattern of the SOCS3 and IL6R Promoters in Rheumatoid Arthritis

• Prif Awduron: Marek Cieśla (Awdur), Bogdan Kolarz (Awdur), Maria Majdan (Awdur), Dorota Darmochwał-Kolarz (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Hindawi Limited, 2020-01-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Interleukin-6 (IL-6) plays an essential function in the development of rheumatoid arthritis (RA), mainly through its proinflammatory effect, which may lead to joint destruction. The genes encoding IL-6 receptor (IL6R) and suppressor of cytokine signaling 3 (SOCS3) play a key role in the IL-6 signali...