A Plasma Proteomic Approach in Rett Syndrome: Classical versus Preserved Speech Variant

• Main Authors: Alessio Cortelazzo (Author), Roberto Guerranti (Author), Claudio De Felice (Author), Cinzia Signorini (Author), Silvia Leoncini (Author), Alessandra Pecorelli (Author), Claudia Landi (Author), Luca Bini (Author), Barbara Montomoli (Author), Claudia Sticozzi (Author), Lucia Ciccoli (Author), Giuseppe Valacchi (Author), Joussef Hayek (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Rett syndrome (RTT) is a progressive neurodevelopmental disorder mainly caused by mutations in the gene encoding the methyl-CpG-binding protein 2 (MeCP2). Although over 200 mutations types have been identified so far, nine of which the most frequent ones. A wide phenotypical heterogeneity is a well-...