Calmodulin Kinase II Activation Is Required for the Maintenance of Basal Activity of L-Type Ca2+ Channels in Guinea-Pig Ventricular Myocytes

• Egile Nagusiak: Li-Ying Hao (Egilea), Jian-Jun Xu (Egilea), Etsuko Minobe (Egilea), Asako Kameyama (Egilea), Masaki Kameyama (Egilea)
• Formatua: Liburua
• Argitaratua: Elsevier, 2008-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The roles of calmodulin (CaM)-dependent protein kinase II (CaMKII) in the maintenance of basal activity and the reversion of run-down of L-type Ca2+ channels were studied in guinea-pig ventricular myocytes by the patch-clamp technique. In the cell-attached configuration, the Ca2+-channel activity wa...