Proteomics-Based Transporter Identification by the PICK Method: Involvement of TM7SF3 and LHFPL6 in Proton-Coupled Organic Cation Antiport at the Blood-Brain Barrier

• मुख्य लेखकों: Toshiki Kurosawa (लेखक), Yuma Tega (लेखक), Yasuo Uchida (लेखक), Kei Higuchi (लेखक), Hidetsugu Tabata (लेखक), Takaaki Sumiyoshi (लेखक), Yoshiyuki Kubo (लेखक), Tetsuya Terasaki (लेखक), Yoshiharu Deguchi (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-08-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

A proton-coupled organic cation (H⁺/OC) antiporter working at the blood-brain barrier (BBB) in humans and rodents is thought to be a promising candidate for the efficient delivery of cationic drugs to the brain. Therefore, it is important to identify the molecular entity that...