Proteomics-Based Transporter Identification by the PICK Method: Involvement of TM7SF3 and LHFPL6 in Proton-Coupled Organic Cation Antiport at the Blood-Brain Barrier

A proton-coupled organic cation (H<sup>+</sup>/OC) antiporter working at the blood-brain barrier (BBB) in humans and rodents is thought to be a promising candidate for the efficient delivery of cationic drugs to the brain. Therefore, it is important to identify the molecular entity that...

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Main Authors: Toshiki Kurosawa (Author), Yuma Tega (Author), Yasuo Uchida (Author), Kei Higuchi (Author), Hidetsugu Tabata (Author), Takaaki Sumiyoshi (Author), Yoshiyuki Kubo (Author), Tetsuya Terasaki (Author), Yoshiharu Deguchi (Author)
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Publicado em: MDPI AG, 2022-08-01T00:00:00Z.
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