Predicting the impact of vaccination on the transmission dynamics of typhoid in South Asia: a mathematical modeling study.

• Main Authors: Virginia E Pitzer (Author), Cayley C Bowles (Author), Stephen Baker (Author), Gagandeep Kang (Author), Veeraraghavan Balaji (Author), Jeremy J Farrar (Author), Bryan T Grenfell (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2014-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Modeling of the transmission dynamics of typhoid allows for an evaluation of the potential direct and indirect effects of vaccination; however, relevant typhoid models rooted in data have rarely been deployed. METHODOLOGY/PRINCIPAL FINDINGS:We developed a parsimonious age-structured model...