Cantharidin Induces Apoptosis and Promotes Differentiation of AML Cells Through Nuclear Receptor Nur77-Mediated Signaling Pathway

• Main Authors: Zanyang Yu (Author), Li Li (Author), Chengqiang Wang (Author), Hui He (Author), Gen Liu (Author), Haoyue Ma (Author), Lei Pang (Author), Mingdong Jiang (Author), Qianwei Lu (Author), Pan Li (Author), Hongyi Qi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundAcute myeloid leukemia (AML) is a hematopoietic malignancy characterized by uncontrolled proliferation and accumulation of myeloblasts in the bone marrow (BM), blood, and other organs. The nuclear receptors Nur77 is a common feature in leukemic blasts and has emerged as a key therapeutic t...