In vitro release of diclofenac diethylamine from gels: evaluation of generic semisolid drug products in Brazil

• Main Authors: Karin Goebel (Author), Mayumi Eliza Otsuka Sato (Author), Dayse Fernanda de Souza (Author), Fábio Seigi Murakami (Author), Itamar Francisco Andreazza (Author)
• Format: Book
• Published: Universidade de São Paulo, 2013-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In order for the pharmacological action of a topical dermal drug product to occur, the drug must first be released from the vehicle to be available to penetrate the skin layers and reach the site of action. Drug release is mainly dependent on the characteristics of the formulation. Currently, to reg...