Cadmium Stimulates the Expression of Vascular Cell Adhesion Molecule-1 (VCAM-1) via p38 Mitogen-Activated Protein Kinase (MAPK) and JNK Activation in Cerebrovascular Endothelial Cells

• Autores principales: Sung Lyea Park (Autor), You-Mie Kim (Autor), Jin-Hee Ahn (Autor), Soo Hwan Lee (Autor), Eun Joo Baik (Autor), Chang-Hyun Moon (Autor), Yi-Sook Jung (Autor)
• Formato: Libro
• Publicado: Elsevier, 2009-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract.: In this study, we examined the effect of Cd on the expression of vascular cell adhesion molecule-1 (VCAM-1) and its mechanisms in bEnd.3 cells. The treatment with Cd increased protein and mRNA expressions of VCAM-1 and increased the phosphorylations of p38, JNK, and ERK. The Cd-induced VC...