Comparison and combination of mutation and methylation-based urine tests for bladder cancer detection

• Main Authors: Naheema S. Gordon (Author), Elspeth K. McGuigan (Author), Michaela Ondasova (Author), Jennifer Knight (Author), Laura A. Baxter (Author), Sascha Ott (Author), Robert K. Hastings (Author), Maurice P. Zeegers (Author), Nicholas D. James (Author), K. K. Cheng (Author), Anshita Goel (Author), Minghao Yu (Author), Roland Arnold (Author), Richard T. Bryan (Author), Douglas G. Ward (Author)
• Format: Book
• Published: BMC, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background and aims Several non-invasive tests for detecting bladder cancer (BC) are commercially available and are based on detecting small panels of BC-associated mutations and/or methylation changes in urine DNA. However, it is not clear which type of biomarker is best, or if a combinati...